Antisuperbugs: 3 million euros for technological innovation in the prevention of resistance of microorganisms to antibiotics

31 May

The healthcare market is one of the areas with the greatest purchasing impact in the public and private sector in Spain with a business turnover of 71 billion euros annually. It is a very complex market where the formulas used for purchasing both consumer goods and drugs, and services depend on the centres themselves. However, they also depend on the local regulations of suppliers, autonomous regions as well as state and community legislation.

This complexity does not only make it impossible for companies to make their products or services available to procurers but it is also often the interested parties in the purchasing that see the inclusion of these produces in their centre and their accessibility to their staff as a truly impossible mission.

And this is a whole lot more difficult when it comes to incorporating new technologies that meet the real needs of professionals.

In a panorama where investment in research and development is at its lowest point in recent decades, having a pre-commercial public procurement project subsidised by the European Union with 3 million euros is a big opportunity for companies that can offer their R+D services to create innovation which responds to the real needs of professionals.

An innovative public procurement project is an approach to innovation based on demand, where a group of procurers combine their resources to share risk in a joint R+D effort in the industry to provide solutions to needs which are not being met by the market. In the case of our project, it would be an ICT solution aimed at the early detection of microorganisms resistant to antibiotics (superbugs) in a healthcare environment, the Antisuperbugs project, coordinated by Jean Patrick Mathieu of the Agency for Health Quality and Assessment of Catalonia (AQuAS).

Antisuperbugs team (from left to right): Kristina Fogel, Sara Bedin, Maren Geissler, Dag Ilver, Benian Ghebremedhin, Jean Patrick Mathieu, Enric Limon, Gonçalo de Carvalho, Gemma Cabré, Esther Arévalo

The consortium coordinated by the AQuAS, an expert institution in the definition and execution of public procurement projects in innovation in Spain, consists of 6 contracting authorities (the Catalan Institute of Oncology IDIBELL (ES), Hospital Mútua of Terrassa (ES), Sheffield Teaching Hospitals NHS Foundation Trust (UK), Helios Kliniken (DE), Universitaetsklinikum Aachen (DE) and Autonomous Province of Trento (IT)), and two expert institutions in their area of research at RISE ACREO (SE) and Sara Bedin (IT).

Enric Limon of the VINCat Programme (Surveillance of Infections) of the CatSalut, principal researcher of the project, sees having a detector of microorganisms resistant to antibiotics as a business opportunity for a company.  In the United States, Asian and European Union markets, solutions are being sought that will make it possible to have a rapid detection system that activates early detection mechanisms. The resistance of certain microorganisms to antibiotics is creating a situation of alarm across the world to which the World Health Organisation (WHO) itself has drawn attention, estimating a figure of 50 million deaths in the years to come if adequate measures are not taken. The successful tendering companies will not only have access to funding but also receive the support of hundreds of professionals from six European institutions at the highest level in research and a potential market in a first phase of hundreds of hospitals and healthcare centres interested in purchasing a solution that they themselves have helped create.

Gonçalo de Carvalho, expert biologist in resistances at the Catalan Institute of Oncology, explains the need for this project to consider the possibility of creating new modules that when applied to the technologies themselves enable new detections to be made which makes purchasing them even more attractive to health institutions by adapting them to their own needs.

The tender which will be opened to companies in the next few months forms part of the Pre-Commercial Public Procurement programmes funded within the European Commission’s H2020 framework of reference. All the information regarding the Antisuperbugs project and the tendering options are available on the website of the project.

Interested companies can access the questionnaire of the open call of the market.

There is also the option for companies to offer their availability by putting in a tender as a consortium.

Post written by Jean Patrick Mathieu, Enric Limon and Gonçalo de Carvalho.

The DECIPHER Project: from the interoperability to the procurement of innovation

8 Jun
Jean Patrick Mathieu

In 2013 when Agència de Qualitat i Avaluació Sanitàries (AQuAS) relaunched the project DECIPHER (@DECIPHERpcpEU), we were pioneering in the field of Procurement of Innovation and little did we know on the journey ahead. The project proved to be a big challenge for the AQuAS, the Catalan Department of Health and the all consortium involved.

The European Commission Officers and the projects evaluators would also be faced with a new type of project and with the projects consortium and stakeholders, we all learned a lot in this exciting adventure.

The journey would end in March 2017 with the Barcelona final event, but the aftermath of the projects will definitely be felt in the years to come.

Rossana Alessandrello at the DECIPHER – FINAL EVENT (Barcelona 2017)

DECIPHER was a project funded by the European Commission under the 7th  Framework Programme (FP7) under a call for project in 2011 whose topic was “Patient Guidance Services (PGS), safety and healthcare record information reuse”.

The objective of the project was to enable secure cross-border mobile access to existing patient healthcare portals which are individually supported by public bodies.

DECIPHER would deploy Pre-commercial Procurement (PCP) to create step-change innovations in mobile patient ICTs. Using electronic patient records as the key enabling technology, this joint PCP would create technology-led service transformation in cross-border mobile healthcare, delivering qualitative and significant benefits to patients and healthcare organisations.

The Consortium consisted of ESTAR Centro (Tuscany), TicSalut (Catalonia) and CMFT (Manchester).  Suppliers will be challenged to build on outputs from epSOS, CALLIOPE, and LOD2, and advances in mobile technology. Moreover, experts from Greece, France, Finland, UK, Sweden and Ireland will provide support.

DECIPHER will generate a portfolio of interoperable applications, deployed on a pan-European platform. This resource will improve existing healthcare services by supporting mobility of patients and healthcare providers.

As a use-case scenario, the solutions were to focus on patients with a chronic health condition and Diabetes type II was selected.

From anywhere in the European Union, a patient will be able to use a secure mobile device safely to gain 24/7 access to their prescription data, emergency data, examination results and other health information.

By the end of the project, 6 prototypes solutions were funded of which 3 finalists received full funding to develop a full final version. Although the respective national Personal Health Records (PHRs) systems of the three procuring authorities are not able to implement those solutions in their current state, the achievements are important for DECIPHER:

  1. Invaluable experiences were gathered by all stakeholders involved in the project
  2. SMEs from all over Europe came under the radar of potential clients, the public procuring authorities in the consortium and those who were interested on the project
  3. AQuAS acquired an expertise in procurement of innovation that is now well-renowned in Europe and beyond.
  4. The lessons learned will be applied in the new PCP project coordinated by AQuAs, Antisuperbugs.

DECIPHER project was initially designed to address the interoperability issue in the healthcare sector. But, this project has been fundamental in the development of a model of procurement of innovation useful for the set-up of this kind of project. With this objective in Catalonia, we consider DECIPHER as a case use where AQuAS lead the path with a set of toolkit, methodology and expertise.

Post written by Jean Patrick Mathieu.